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Alan Stern

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Alan Stern
Staff Computational Scientist
Rowland Institute at Harvard
Harvard University
100 Edwin H. Land Blvd.
Cambridge, MA 02142
Tel: 617-497-4684
Fax: 617-497-4627
Email: stern@rowland.harvard.edu


Education

  • University of California, Berkeley, Ph.D. (Mathematics), 1984


  • Harvard University, A.B. (Mathematics, summa cum laude), 1979

Publications

  • Shimba N, Kovacs H, Stern AS, Nomura AM, Shimada I, Hoch JC, Craik CS, Dotsch V. “Optimization of (13)C direct detection NMR methods.” J Biomol NMR, 30, 175-179 (2004)


  • Rovnyak D, Hoch JC, Stern AS, Wagner G. “Resolution and sensitivity of high field nuclear magnetic resonance spectroscopy.” J Biomol NMR, 30, 1-10 (2004)


  • Rovnyak D, Frueh DP, Sastry M, Sun ZY, Stern AS, Hoch JC, Wagner G. “Accelerated acquisition of high resolution triple-resonance spectra using non-uniform sampling and maximum entropy reconstruction.” J Magn Res, 170, 15-21 (2004)


  • Connolly PJ, Stern AS, Turner CJ, Hoch JC “Molecular dynamics of the long neurotoxin LSIII”, Biochemistry, 42, 14443-51 (2003)


  • Shimba N, Stern AS, Craik CS, Hoch JC, Dotsch V. “Elimination of 13Calpha splitting in protein NMR spectra by deconvolution with maximum entropy reconstruction” J Am Chem Soc., 125 2382-3 (2003)


  • Rovnyak D, Filip C, Itin B, Stern AS, Wagner G, Griffin RG, Hoch JC. “Multiple-quantum magic-angle spinning spectroscopy using nonlinear sampling”, J. Magn. Reson., 161, 43-55 (2003)


  • F. Offredi, F. Dubali, P. Kischel. K. Sarinski, Alan S. Stern, C. Van de Weerdt, Jeffrey C. Hoch, C. Prosperi, J.M. François, S.L. Mayo, and J.A. Martial “De novo Backbone and Sequence Design of an Idealized alpha/beta- barrel Protein: Evidence of Stable Tertiary Structure”, J. Mol. Biol., 325, 163-174 (2003)


  • Alan S. Stern, Kuo-Bin Li, and Jeffrey C. Hoch “Modern spectrum analysis in multidimensional NMR spectroscopy. Comparison of linear-prediction extrapolation and maximum-entropy reconstruction”, J. Am. Chem. Soc., 124, 1982-1993 (2002)


  • Jeffrey C. Hoch and Alan S. Stern “Maximum Entropy Reconstruction, Spectrum Analysis and Deconvolution in Multidimensional Nuclear Magnetic Resonance”, Meth. Enzym., 338, 159-178 (2001)


  • Jeffrey C. Hoch and Alan S. Stern “Signatures and Consequences of Hydrophobic Strain in Globular Proteins”, in “Dynam., Struc., and Func. Biol. Macromol.” O. Jardetzky and M.D. Finucane, eds., IOS Press, Amsterdam, (2001)


  • Zach Serber, Christian Richter, Detlef Moskau, Jean-Marc Böhlen, Tobias Gerfin, Daniel Marek, Markus Häberli, Ludivica Baselgia, Frank Laukien, Alan S. Stern, Jeffrey C. Hoch, and Volker Dötsch “New Carbon-Detected Protein NMR Experiments Using CryoProbes”, J. Am. Chem. Soc., 122, 3554-3555 (2000)


  • Linda Turner, Arivinathan D.T. Samuel, Alan S. Stern and Howard C. Berg “Temperature dependence of switching of the bacterial flagellar motor by the protein CheY(13DK106YW)”, Biophys. J., 77, 597-603 (1999)


  • C.J. Turner, Peter J. Connolly and Alan S. Stern “Artifacts in sensitivity-enhanced HSQC.”, J. Magn. Reson. 137, 281-284 (1999)


  • Jeffrey C. Hoch and Alan S. Stern “Fitting Protein Structures to Experimental Data: Lessons from Before Your Mother Was Born”, in “Protein Dynamics, Function, and Design”, O. Jardetzky and J.-F. Lefevre, eds., Plenum Press, New York (1998)


  • Kuo-Bin Li, Alan S. Stern, Jeffrey C. Hoch “Distributed parallel processing for multidimensional maximum entropy reconstruction”, J Magn Reson., 134 161-163 (1998)


  • Peter Schmieder, Alan S. Stern, Gerhard Wagner, and Jeffrey C. Hoch “Quantification of Maxium-Entropy Spectrum Reconstructions”, J. Magn. Reson, 125, 332-339 (1997)


  • Edgar Jacoby, Qing Xin Hua, Alan S. Stern, Bruce H. Frank, and Michael A. Weiss “Structure and Dynamics of a Protein Assembly. 1H-NMR Studies of the 36 kDa R6 Insulin Hexamer”, J. Mol. Biol., 258, 136-157 (1996)


  • Alan S. Stern and Jeffrey C. Hoch “Maximum Entropy Reconstruction in NMR”, in Encyclopedia of NMR, D. M. Grant and R. K. Harris, eds., John Wiley & Sons, Chichester (1996)


  • Peter J. Connolly, Alan S. Stern and Jeffrey C. Hoch “Solution Structure of LSIII, a Long Neurotoxin from the Venom of Laticauda semifasciata”, Biochemistry, 35, 418-426 (1996)


  • Peter J. Connolly, Alan S. Stern, and Jeffrey C. Hoch “Solution Structure of the Long Neurotoxin LSIII, With Possible Implications for Binding to the Acetylcholine Receptor”, in Dynamics and the Problem of Recognition in Biological Macromolecules, O. Jardetzky and F.-F. Lefevre, eds., Plenum Press, New York (1996)


  • Peter Schmieder, Alan S. Stern, Gerhard Wagner, and Jeffrey C. Hoch “Improved Resolution in Triple-Resonance Spectra by Nonlinear Sampling in the Contant-Time Domain”, J. Biomol. NMR, 4, 483- 490 (1994)


  • Alan S. Stern and Stanislaw S. `Swierczkowski “A Class of Connected Theories of Order”, J. Symb. Logic, 59, 534-542 (1994)


  • Peter J. Connolly, Alan S. Stern and Jeffrey C. Hoch “Estimating Protein Fold from Incomplete and Approximate NMR Data”, J. Am. Chem. Soc, 116, 2675-2676 (1994)


  • George J. Maalouf, Jeffrey C. Hoch, Alan S. Stern, Hanna Szöke, and Abraham Szöke “Holographic Methods in X-ray Crystallography. III. First Numerical Results”, Acta Cryst., A49, 866-871 (1993)


  • Peter Schmieder, Alan S. Stern, Gerhard Wagner, and Jeffrey C. Hoch “Application of Nonlinear Sampling Schemes to COSY-type Spectra”, J. Biomol. NMR, 3, 569-576 (1993)


  • Alan S. Stern “Construction of Sentences with Specific Interpretability Properties”, Fund. Math., 142, 189-200 (1993)


  • Jeffrey C. Hoch and Alan S. Stern “A Method for Determining Overall Protein Fold from NMR Distance Restraints”, J. Biomol. NMR, 2, 535-543 (1992)


  • Alan S. Stern and Jeffrey C. Hoch “A New, Storage-Efficient Algorithm for Maxium Entropy Spectrum Reconstruction”, J. Magn. Reson., 97, 97-250 (1992)


  • David L. Donoho, Iain M. Johnstone, Jeffrey C. Hoch, and Alan S. Stern “Maxium Entropy and the Nearly Black Object”, J. R. Statist. Soc. B, 54, 41-81 (1992)


  • Jeffrey C. Hoch, Alan S. Stern, and Christina Redfield “Computer-Aided Analysis of Protein NMR Spectra”, Current Opinion in Structural Biology, 1, 1036-1041 (1992)


  • David L. Donoho, Iain M. Johnstone, Alan S. Stern, and Jeffrey C. Hoch “Does the Maxium Entropy Method Improve Sensitivity?”, Pro. Natl. Acad. Sci. USA, 87, 5066-5068 (1990)


  • Jan Mycielski, Pavel Pudlák, and Alan S. Stern “Maxium Entropy Reconstruction of Complex (Phase-Sensitive) Spectra”, Memoirs of the American Mathematical Society, 426, American Mathematical Society, Providence (1990)


  • Alan S. Stern “Sequential Theories and Infinite Distributivity in the Lattice of Chapters”, J. Symb. Logic, 54, 190-206 (1989)


  • Alan S. Stern “The Lattice of Local Interpretability of Theories”, Ph.D. dissertation, University of California, Berkeley (1984)